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Table 2 Number of genes involved in the transfer from adipocytes to macrophages, those possibly mediated by exosomes, and their overlap significance

From: A next generation sequencing based approach to identify extracellular vesicle mediated mRNA transfers between cells

  # transcripts measured in ADMOexosome # Sig Genea FPKM > 0 FPKM > 1
Allb overlap p-valuec all overlap p-value
AD to MO 60,566 20 13,697 17 <2.2E-16 1966 5 < 2.2E-16
MO to AD 60,566 8 13,697 8 <2.2E-16 1966 2 < 2.2E-16
  1. aThe significant gene is defined at FDR < = 0.05
  2. bAll (overlap) denotes the number of transcripts with FPKM > 0 (and overlapping with significant genes) for ADMOexosome
  3. cThe p-value is obtained by testing the overlapping significance between “All” and “Sig Gene” using the Fisher’s exact test with all 60,566 transcripts measured as background