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Table 3 Top loci identified as transferred from adipocyte to macrophage

From: A next generation sequencing based approach to identify extracellular vesicle mediated mRNA transfers between cells

Location Gene Symbol AD GTa MO GT Allele Typeb MOcoN1 MOcoN2 MOcoN3 MOalone Count FDR ADMOexosome FPKMd
BFc Count BF Count BF Count
chr16:88,718,047 PIEZO1 C/C T/T T|C 2.19E + 13 6|5 5.25E + 03 17|2 1.07E + 07 40|4 24 2.78E-06 2.21E-01
chr9:35,657,841 RMRP A/G G/G G|A|T|C|N 1.69E + 32 1917|25|1|0|0 8.25E + 02 20,459|18|6|5|1 1.05E + 03 22,090|19|14|4|0 21,575|10|1|5|0 8.41E-06 1.89E-01
chr1:183,136,570 LAMC1 A/G G/G G|A 1.97E + 02 82|2 1.03E + 07 92|4 2.06E + 01 141|2 92 7.65E-05 1.64E-01
chr19:7,692,417 FCER2 T/C T/T T|C 8.00E + 00 29|1 1.34E + 02 26|2 1.36E + 03 40|3 49 6.12E-04 6.45E-01
chr6:75,666,836 SENP6 G/G A/A A|G|C 6.08E + 05 39|4|0 1.42E + 01 171|2|0 2.60E + 00 224|2|1 131 1.57E-03 1.08E + 00
chr14:77,575,179 SPTLC2 T/C T/T T|C 5.67E + 09 8|4 NA NA 3.72E + 23 23|10 6 1.59E-03 5.10E-01
chr6:159,682,052 SOD2 T/C C/C C|T 7.03E + 02 67|2 6.04E + 00 269|2 2.33E + 00 507|2 135 6.30E-03 1.76E + 00
chr4:102,344,186 SLC39A8 A/C C/C C|A 1.67E + 04 17|2 1.16E-01 12 1.63E + 03 50|2 13 6.40E-03 1.48E + 00
chr20:17,607,288 DSTN G/G A/A A|G 4.13E + 03 11|2 1.44E + 06 124|5 3.29E-02 297|1 163 9.72E-03 1.33E + 00
chr20:41,180,020 ZHX3 G/G T/T T|G 5.58E + 00 11|1 1.49E + 02 27|2 5.96E-01 67|1 30 1.42E-02 5.09E-01
chr13:29,766,448 UBL3 T/C T/T T|C 4.14E-01 60|1 1.74E + 00 135|2 6.74E + 00 104|2 107 1.90E-02 2.22E-01
chr14:75,278,923 FOS T/C T/T T|C 9.20E-01 89|1 7.94E-01 398|2 6.82E + 00 542|3 288 2.68E-02 2.60E-01
chr4:119,217,669 USP53 A/G A/A A|G 1.08E-01 13 6.08E + 01 41|2 1.42E + 02 42|2 14 3.28E-02 8.99E-02
chr16:68,095,198 NFATC3 A/A G/G G|A NA NA 5.09E + 02 8|2 4.85E + 09 20|4 4 3.99E-02 1.39E + 00
chr4:48,586,725 FRYL C/C T/T T|C 1.08E + 00 39|1 3.81E-01 67|1 4.48E + 00 127|2 53 4.10E-02 6.71E-01
chr11:62,524,481 AHNAK T/A A/A A|T 2.45E + 01 14|1 2.34E + 00 111|1 2.14E-01 333|1 214 4.37E-02 2.89E-01
chr10:32,925,874 ITGB1 A/A G/G G|A 8.20E-02 178|2 3.23E + 01 484|3 2.70E + 02 912|6 482|1 9.04E-02 5.15E-01
  1. a ADGT (MOGT) denotes the genotype of adipocyte (macrophage) detected by SNP array
  2. b AlleleType (Count) denotes all alleles (the number of alleles) mapped at the corresponding location by the RNA-seq data on replicated samples
  3. c The Bayesian factor calculated at the specific locus for the corresponding sample
  4. d The fpkm value of the gene at ADMOexosome as quantified by Cufflinks