Fig. 2
From: The variome of pneumococcal virulence factors and regulators
Chromosomal localization and direction of the virulence factor genes of S. pneumoniae TIGR4. Lineal representation of the pneumococcus genome. The arrows, drawn at scale, localize 62 of the 65 virulence factors and simple regulation genes considered in this study (pitA, pitB and zmpD are not present in the genome of TIGR4). Each color represents a different class of codified protein: blue = sortase-anchored proteins with an LPxTG cleavage motif; violet = choline-binding proteins (CBPs); green = lipoproteins, yellow = non-classical surface proteins (NCSP), and red = stand-alone regulators. This map was constructed using the Software SnapGene® (GSL Biotech; Available at snapgene.com)