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Table 4 Top 3 transcripts for the top modules for each trait

From: Resistant and susceptible chicken lines show distinctive responses to Newcastle disease virus infection in the lung transcriptome

Trait

Module

Top 3 Transcripts (description)

(GSa, MMb)

Line

Blue

ENSGALT00000052188 (lincRNA)

ENSGALT00000087010 (protein coding)

ENSGALT00000066798 (lincRNA)

(0.976, 0.964)

(0.976, 0.966)

(0.974, 0.962)

cDPI

Darkturquoise

RNF208 (Ring finger protein 208)

LAMA2 (Laminin subunit alpha 2)

LCK (LCK proto-oncogene, Src family tyrosine kinase)

(0.644, 0.753)

(−0.644, −0.562)

(0.643, 0.74)

Treatment

Black

cNFI-A (Nuclear factor 1 C-type)

RHOT2 (Ras homolog family member T2)

UBE2E3 (Ubiquitin conjugating enzyme E2 E3)

(−0.671, 0.694)

(0.61, −0.827)

(−0.576, 0.812)

Sex

Lightyellow

ENSGALT00000077789 (Nipped-B homolog-like)

ENSGALT00000085229 (lincRNA)

ENSGALT00000080994 (protein coding)

(−0.987, −0.937)

(−0.985, −0.94)

(−0.984, −0.964)

2 dpi viral load

Black

cNFI-A (Nuclear factor 1 C-type)

RHOT2 (Ras homolog family member T2)

CDC5L (Cell division cycle 5 like)

(−0.648, 0.694)

(0.596, −0.827)

(−0.586, 0.681)

6 dpi viral load

Skyblue

FAM98B (Family with sequence similarity 98 member B)

FUT8 (Alpha-(1,6)-fucosyltransferase)

ATP6V1H (V-type proton ATPase subunit H)

(−0.609, 0.777)

(−0.605, 0.87)

(−0.592, 0.849)

10 dpi antibody level

Darkred

ENSGALT00000068419 (protein coding)

FSTL1 (Follistatin like 1)

NOV (Nephroblastoma overexpressed)

(−0.754, 0.895)

(−0.729, 0.844)

(−0.719, 0.794)

  1. aGene Significance (GS)
  2. bModule Membership (MM)
  3. cDays post infection (DPI)