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Fig. 3 | BMC Genomics

Fig. 3

From: Transcriptome analyses of immune tissues from three Japanese frogs (genus Rana ) reveals their utility in characterizing major histocompatibility complex class II

Fig. 3

Phylogenetic relationships between MHC-IIB variants (amino acid sequences) identified in R. japonica (Raja), R. ornativentris (Raor), and R. t. tagoi (Rata) and other amphibians using neighbour-joining method and 1000 bootstrap replicates. Phylogenies were constructed based from (a) entire β1 domain encoded by exon 2, and (b) entire β2 domain encoded by exon 3. Nodes with bootstrap support >70% are indicated. Accession numbers from other species are indicated on labels, and ‘tr’ indicates sequences obtained from transcriptomic data of R. pirica (Mori, T., unpublished) and L. catesbeianus (DRA accession number SRP051787). The unique variant Rata-01, which clusters differently in each exon, is emphasised by a box. Supertypes allocated to β1 domain variants are indicated by coloured lines; other species used for supertype analyses are not included due to incomplete sequences

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