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Table 3 Mean (SD) 1500 m, 5000 m, 10,000 m and marathon best running times in males within 20% of the world record in (a) the three ACTN3 R577X genotypes and (b) the three ACE I/D genotypes

From: No association between ACTN3 R577X and ACE I/D polymorphisms and endurance running times in 698 Caucasian athletes

(a)
ACTN3R577X males RR
N = 296
37.0%
RX
N = 340
42.6%
XX
N = 163
20.4%
Additive
(RR = 0, RX = 1, XX = 2)
Recessive
(RR = RX = 0, XX = 1)
 Running time 1500 m (s) 230.8 (7.5)
44.2%
230.0 (8.1)
38.0%
228.7 (11.8)
17.8%
p = 0.34 p = 0.42
 Running time 3000 m (s) 497.0 (16.2)
38.3%
502.2 (16.6)
42.8%
503.1 (18.8)
18.9%
p = 0.08 p = 0.37
 Running time 5000 m (s) 857.5 (29.9)
34.6%
861.2 (30.2)
45.0%
861.7 (31.2)
20.4%
p = 0.52 p = 0.76
 Running time 10,000 m (s) 1789.4 (66.0)
36.8%
1776.8 (66.6)
42.4%
1788.7 (70.7)
20.8%
p = 0.83 p = 0.76
 Running time marathon (s) 8502.7 (330.0)
33.3%
8471.5 (302.1)
43.1%
8462.0 (337.8)
23.6%
p = 0.64 p = 0.76
(b)
ACE I/Dmales DD
N = 229
33.7%
ID
N = 306
45.0%
II
N = 145
21.3%
Additive
(DD = 0, ID = 1, II = 2)
Recessive
(DD = ID = 0, II = 1)
 Running time 1500 m (s) 228.1 (11.0)
29.2%
231.6 (8.0)
46.9%
232.1 (8.2)
24.0%
p = 0.11 p = 0.39
 Running time 3000 m (s) 501.8 (16.9)
34.0%
502.1 (18.3)
43.3%
505.3 (17.0)
22.7%
p = 0.49 p = 0.42
 Running time 5000 m (s) 866.9 (29.2)
34.4%
861.5 (33.7)
45.9%
858.6 (29.2)
19.7%
p = 0.32 p = 0.52
 Running time 10,000 m (s) 1795.5 (66.8)
35.5%
1789.8 (73.2)
47.7%
1786.4 (64.8)
16.8%
p = 0.70 p = 0.79
 Running time marathon (s) 8495.1 (287.9)
34.1%
8507.6 (343.5)
42.9%
8457.5 (327.6)
22.9%
p = 0.79 p = 0.64
  1. All running times are expressed in seconds because statistics were performed on times converted to seconds. The last two columns of the table correspond to the p-value of the linear regression, using an additive or a recessive genetic model. The percentage values represent the genotype proportions