Table 3 Mean (SD) 1500 m, 5000 m, 10,000 m and marathon best running times in males within 20% of the world record in (a) the three ACTN3 R577X genotypes and (b) the three ACE I/D genotypes

RR

N = 296

37.0%

RX

N = 340

42.6%

XX

N = 163

20.4%

Additive

(RR = 0, RX = 1, XX = 2)

Recessive

(RR = RX = 0, XX = 1)

230.8 (7.5)

44.2%

230.0 (8.1)

38.0%

228.7 (11.8)

17.8%

p = 0.34

p = 0.42

497.0 (16.2)

38.3%

502.2 (16.6)

42.8%

503.1 (18.8)

18.9%

p = 0.08

p = 0.37

857.5 (29.9)

34.6%

861.2 (30.2)

45.0%

861.7 (31.2)

20.4%

p = 0.52

p = 0.76

1789.4 (66.0)

36.8%

1776.8 (66.6)

42.4%

1788.7 (70.7)

20.8%

p = 0.83

p = 0.76

8502.7 (330.0)

33.3%

8471.5 (302.1)

43.1%

8462.0 (337.8)

23.6%

p = 0.64

p = 0.76

DD

N = 229

33.7%

ID

N = 306

45.0%

II

N = 145

21.3%

Additive

(DD = 0, ID = 1, II = 2)

Recessive

(DD = ID = 0, II = 1)

228.1 (11.0)

29.2%

231.6 (8.0)

46.9%

232.1 (8.2)

24.0%

p = 0.11

p = 0.39

501.8 (16.9)

34.0%

502.1 (18.3)

43.3%

505.3 (17.0)

22.7%

p = 0.49

p = 0.42

866.9 (29.2)

34.4%

861.5 (33.7)

45.9%

858.6 (29.2)

19.7%

p = 0.32

p = 0.52

1795.5 (66.8)

35.5%

1789.8 (73.2)

47.7%

1786.4 (64.8)

16.8%

p = 0.70

p = 0.79

8495.1 (287.9)

34.1%

8507.6 (343.5)

42.9%

8457.5 (327.6)

22.9%

p = 0.79

p = 0.64