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Table 2 Genes with ≥20 fold-change in at least two time points for PMA exposure (n = 17)

From: Transcriptional responses of Escherichia coli during recovery from inorganic or organic mercury exposure

Gene ID Gene Name Product Description Hg t10 Hg t30 Hg t60 PMA t10 PMA t30 PMA t60
b3728 pstS ABC phosphate transport system; periplasmic binding protein n.s. 16 8 86 165 n.s.
b1020 phoH ATP-binding protein, function unknown 8 71 221 61 365 n.s.
b0996 torC* c-Type cytochrome n.s. n.s. n.s. 55 65 77
b4060 yjcB Function unknown 33 11 12 52 35 n.s.
b0399 phoB Positive response regulator for pho regulon 4 22 3 51 105 n.s.
b1530 marR Transcription repressor of multiple antibiotic resistance 26 7 n.s. 48 29 n.s.
b1531 marA Transcriptional activator for multiple antibiotic resistance; 15 9 n.s. 46 31 n.s.
b1112 bhsA Biofilm, cell surface and signaling defects, YhcN family 1949 563 94 46 21 n.s.
b1532 marB marRAB multiple antibiotic resistance operon 16 8 n.s. 45 27 n.s.
b4663 azuC Function unknown; membrane-associated 27 25 36 41 49 n.s.
b4030 psiE Pho regulon, regulated by phoB and cAMP 35 64 17 38 59 n.s.
b3686 ibpB Chaperone, heat-inducible protein of HSP20 family 402 124 281 37 211 9
b1748 astC Succinylornithine transaminase; carbon starvation protein 30 31 25 34 36 n.s.
b3469 zntA Zn(II), Cd(II), and Pb(II) translocating P-type ATPase 40 19 8 29 22 n.s.
b2582 trxC Thioredoxin 2, zinc-binding; Trx2 134 50 7 24 24 n.s.
b4354 yjiY Predicted transporter, function unknown n.s. n.s. n.s. 20 77 n.s.
b1625 cnu OriC-binding complex H-NS/Cnu n.s. 10 n.s. 20 24 n.s.
  1. Table is sorted by PMA at 10 min column. n.s. = not significantly different from unexposed culture and boldface highlights actual values ≥20-fold. Gene names in boldface have a ≥ 20 differential expression response to both Hg and PMA in at least one time point (n = 11). Genes marked with an asterisk (*) had fewer than 11 average read counts for at least 2 time points in the unexposed condition and were operationally defined as being “off” in that condition. Such genes constituted, the lowest 15th percentile of all genes, based on raw read counts normalized across all libraries and across all biological replicates