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Table 1 Alignment of WES data from the human-mouse DNA dilution series

From: Computational approach to discriminate human and mouse sequences in patient-derived tumour xenografts

% of human DNA %of mouse DNA Replicate Alignment efficiency human genome % Alignment efficiency combined genome (%) %of reads mapped on the human genome %of reads mapped on the mouse genome Estimated human DNA content
100 0 a 90.81 90.64 99.98 0.02 99.89
100 0 b 90.38 90.16 99.98 0.02 99.88
100 0 c 90.26 90.13 99.98 0.02 99.89
90 10 a 88.57 90.43 97.59 2.41 90.22
90 10 b 88.53 90.39 97.58 2.42 90.16
50 50 a 75.65 89.37 83.14 16.86 50.73
50 50 b 74.90 89.71 82.18 17.82 49.01
50 50 c 75.41 89.55 82.78 17.22 50.07
25 75 a 58.07 89.25 62.44 37.56 23.97
25 75 b 60.25 89.48 64.58 35.42 26.17
0 100 a 7.01 88.77 0.10 99.90 0.00
0 100 b 7.17 88.56 0.10 99.90 0.00
0 100 c 6.65 88.95 0.08 99.92 0.00