Fig. 2

Unique dual-matched sample indices reduce read misassignment caused by contamination. a Example contamination of A1 adapter with 1% of A2 adapter. Because only the i7 index is used to discriminate between the samples, 1% of sample A1 reads would be misassigned to sample A2. b The same 1% level of contamination with unique dual-matched indexed adapters results in only 0.01% read misassignment to sample A2