Skip to main content

Advertisement

Table 2 Ten most significant differentially methylated regions associated with migraine

From: Genome-wide DNA methylation profiling in whole blood reveals epigenetic signatures associated with migraine

Chromosome Start (bp) End (bp) Direction P value FDR No. of Probes RefSeq gene(s)
11 20,625,538 20,628,781 Decrease 2.54 × 10− 17 4.16 × 10− 12 10 SLC6A5
6 30,033,321 30,046,936 Decrease 1.50 × 10− 14 1.23 × 10− 9 128 PPP1R11, RNF39
9 124,987,896 124,992,432 Increase 1.65 × 10− 12 8.99 × 10−8 13 LHX6
3 185,911,208 185,913,486 Decrease 5.28 × 10−12 2.16 × 10−7 9 DGKG
13 31,506,270 31,508,139 Decrease 2.15 × 10−11 7.04 × 10−7 11 TEX26, TEX26-AS1
11 67,417,958 67,419,405 Decrease 6.54 × 10−10 1.79 × 10− 5 13 ACY3
5 156,886,147 156,888,490 Decrease 1.26 × 10−9 2.95 × 10− 5 12 LOC102724404, NIPAL4
6 74,070,966 74,075,136 Increase 1.99 × 10−9 4.08 × 10− 5 16 KHDC3L
12 52,403,511 52,405,422 Decrease 2.65 × 10−9 4.34 × 10− 5 6 GRASP
13 31,479,366 31,482,184 Decrease 2.46 × 10−9 4.34 × 10−5 13 MEDAG, TEX26-AS1