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Table 3 Association statistics for methylation probes within the most significant differentially methylated region

From: Genome-wide DNA methylation profiling in whole blood reveals epigenetic signatures associated with migraine

Summary statistics Probe expression Annotation
Chromosome Position (bp) Probe Coef. SE P value β value Change Feature Gene
11 20,625,538 cg07428491 −1.8326 0.8211 0.0208 0.5062 −0.0168 Shelf SLC6A5
11 20,625,714 cg15083015 −1.7232 0.6336 0.0021 0.5019 −0.0318 Shelf SLC6A5
11 20,625,992 cg04968806 −5.1739 1.7130 0.0013 0.5024 −0.0114 Shelf SLC6A5
11 20,626,133 cg21957058 −1.6045 0.6913 0.0149 0.5045 −0.0209 Shelf SLC6A5
11 20,626,264 cg09357935 −1.4053 0.4701 0.0009 0.5031 −0.0453 Shelf SLC6A5
11 20,626,786 cg15828364 −2.1671 0.8315 0.0050 0.5062 −0.0209 Shelf SLC6A5
11 20,627,025 cg23745839 −1.3968 0.5961 0.0146 0.5042 −0.0229 Shelf SLC6A5
11 20,627,327 cg18042724 −2.7853 0.8116 0.0000 0.5069 −0.0374 Shelf SLC6A5
11 20,627,597 cg14524936 −3.6597 1.0867 0.0002 0.5011 −0.0225 Sea SLC6A5
11 20,627,781 cg19172170 −3.0185 1.0297 0.0016 0.5035 −0.0187 Sea SLC6A5
  1. Notes: Coef. denotes the regression coefficient, derived from a general linear model. A negative coefficient indicates lower probe expression in cases relative to controls. β value indicates the mean probe beta value, and change represents the mean difference in probe expression between cases and controls. Feature shows the position of each probe relative to CpG Islands—genomic regions in which the frequency of CpG sites is higher than other regions