Skip to main content

Table 3 Association statistics for methylation probes within the most significant differentially methylated region

From: Genome-wide DNA methylation profiling in whole blood reveals epigenetic signatures associated with migraine

Summary statistics

Probe expression

Annotation

Chromosome

Position (bp)

Probe

Coef.

SE

P value

β value

Change

Feature

Gene

11

20,625,538

cg07428491

−1.8326

0.8211

0.0208

0.5062

−0.0168

Shelf

SLC6A5

11

20,625,714

cg15083015

−1.7232

0.6336

0.0021

0.5019

−0.0318

Shelf

SLC6A5

11

20,625,992

cg04968806

−5.1739

1.7130

0.0013

0.5024

−0.0114

Shelf

SLC6A5

11

20,626,133

cg21957058

−1.6045

0.6913

0.0149

0.5045

−0.0209

Shelf

SLC6A5

11

20,626,264

cg09357935

−1.4053

0.4701

0.0009

0.5031

−0.0453

Shelf

SLC6A5

11

20,626,786

cg15828364

−2.1671

0.8315

0.0050

0.5062

−0.0209

Shelf

SLC6A5

11

20,627,025

cg23745839

−1.3968

0.5961

0.0146

0.5042

−0.0229

Shelf

SLC6A5

11

20,627,327

cg18042724

−2.7853

0.8116

0.0000

0.5069

−0.0374

Shelf

SLC6A5

11

20,627,597

cg14524936

−3.6597

1.0867

0.0002

0.5011

−0.0225

Sea

SLC6A5

11

20,627,781

cg19172170

−3.0185

1.0297

0.0016

0.5035

−0.0187

Sea

SLC6A5

  1. Notes: Coef. denotes the regression coefficient, derived from a general linear model. A negative coefficient indicates lower probe expression in cases relative to controls. β value indicates the mean probe beta value, and change represents the mean difference in probe expression between cases and controls. Feature shows the position of each probe relative to CpG Islands—genomic regions in which the frequency of CpG sites is higher than other regions