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Table 4 Pathway analysis of hypomethylated DMR-associated genes in migraine

From: Genome-wide DNA methylation profiling in whole blood reveals epigenetic signatures associated with migraine

Reactome pathway Size Overlap FDR Genes
SLC-mediated transport 272 3 5.00 × 10−2 SLC2A9, SLC38A4, SLC6A5
Transport of glucose 102 2 5.43 × 10−2 SLC2A9, SLC6A5
Haemostasis 599 4 8.84 × 10−2 DGKG, KIF26A, DOCK6, CFD
  1. Notes: Reactome pathway names truncated for presentation purposes. Full pathway annotation ordered by significance: R-HSA-425407 (LC-mediated transmembrane transport); R-HSA-425366 (Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds); R-HSA-109582 (Haemostasis); R-HSA-983231 (Factors involved in megakaryocyte development and platelet production); and R-HSA-382551 (Transmembrane transport of small molecules)