Fig. 4

GRIM-Filter integration with a read mapper. The Filter Bitmask Generator uses the bitvectors for each bin to determine whether any locations within the bin are potential matches with the read sequence, and saves potential match information into a Seed Location Filter Bitmask. The Seed Location Checker uses the bitmask to retrieve the corresponding reference segments for only those seed locations that match, which are then sent to the read mapper for sequence alignment