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Fig. 2 | BMC Genomics

Fig. 2

From: Identification of usual interstitial pneumonia pattern using RNA-Seq and machine learning: challenges and solutions

Fig. 2

Gene selection using DESeq2 and our classifier. a Volcano plot showing 151 genes selected by DESeq2 (adjusted p-value < 0.05 and fold change > 2) and 190 predictive genes in our classifier, with 32 common ones (pink) between the two sets of genes. b PCA plot of all TBB samples using only DESeq2 selected genes showing that these genes are not sufficient to separate UIP samples (orange circle) from non-UIP samples (blue cross). c PCA plot of all TBB samples using classifier genes illustrating that TBB samples can be classified into UIP (orange circle) and non-UIP (blue cross) samples using these genes

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