Skip to main content

Table 2 Enrichment by various types of functional interactions in groups of differentially expressed proteins in thyroid cancer (dbDEPC) estimated with FunGeneNet

From: FunGeneNet: a web tool to estimate enrichment of functional interactions in experimental gene sets

Experiment

ANDSystem interaction type

p-value

BH correcteda p-value

E39

all types

3.83E-03

(1.47e-17)

1.84E-02

E39

activity and transport regulation

1.58E-01

3.45E-01

E39

catalysis

6.56E-01

7.50E-01

E39

coexpression

6.08E-01

7.50E-01

E39

expression regulation

7.27E-01

7.93E-01

E39

interaction

4.62E-01

7.06E-01

E50

all types

2.02E-02

(6.31e-05)

8.08E-02

E50

activity and transport regulation

1.09E-01

2.91E-01

E50

catalysis

1.45E-05

1.74E-04

E50

coexpression

5.00E-01

7.06E-01

E50

expression regulation

6.56E-01

7.50E-01

E50

interaction

6.58E-02

1.97E-01

E50 ∩ E39

all types

4.36E-01

(3.52E-03)

7.06E-01

E50 ∩ E39

activity and transport regulation

1.35E-01

3.24E-01

E50 ∩ E39

catalysis

5.00E-01

7.06E-01

E50 ∩ E39

coexpression

5.00E-01

7.06E-01

E50 ∩ E39

expression regulation

5.69E-01

7.50E-01

E50 ∩ E39

interaction

7.84E-01

8.18E-01

E50 ∪ E39

all types

6.42E-06

(3.48e-29)

1.54E-04

E50 ∪ E39

activity and transport regulation

4.03E-01

7.06E-01

E50 ∪ E39

catalysis

1.11E-04

8.88E-04

E50 ∪ E39

coexpression

1.19E-03

7.14E-03

E50 ∪ E39

expression regulation

8.89E-01

8.89E-01

E50 ∪ E39

interaction

4.71E-02

1.61E-01

  1. p < 0.001 are highlighted in bold
  2. STRING p-values are given in parentheses
  3. aBenjamini-Hochberg correction, see methods