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Fig. 7 | BMC Genomics

Fig. 7

From: Transcription start site profiling uncovers divergent transcription and enhancer-associated RNAs in Drosophila melanogaster

Fig. 7

Analysis of E-nuTSS distribution and overlap with known enhancers. a Genomic distribution of nuTSSs in different histone PTM-based clusters. “Enhancer-like” (nuTSS cluster 7) start sites occur disproportionately in intergenic and intronic regions. b Consensus motif at Cluster 7 nuTSSs. c Overlap between Flylight enhancers validated for expression in larval CNS or imaginal discs (yellow, 3179) and nuTSSs from Cluster 5 (red, 1296) or cluster 7 (blue, 715). d Histogram describing number of nuTSSs overlapping validated FlyLight enhancers in 5000 randomly shuffled trials (grey) vs. the number of Cluster 7 nuTSSs overlapping experimentally (red line). e Overlap between Flylight enhancers validated for expression in larval CNS or imaginal discs (yellow, 3179) and ATAC-seq peaks (Green, 38,698)

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BMC Genomics

ISSN: 1471-2164

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