Fig. 3

Structure-based models improve in vivo binding prediction. a) HRHNPK in vivo binding prediction improves AUC from 0.75 to 0.81. Sequence preferences agree with a previous study, but no structural preferences were previously known. b) PUM2 in vivo binding prediction improves AUC from 0.52 to 0.59. Sequence and structural preferences agree with previously-published preferences based on PAR-CLIP data inferred by GraphProt algorithm. Structural contexts letter: S = stem / paired, H = hairpin loop, I = inner loop, M = multi loop, E = external region