TY - JOUR AU - de Oliveira, Tássio Brito AU - Gostinčar, Cene AU - Gunde-Cimerman, Nina AU - Rodrigues, Andre PY - 2018 DA - 2018/02/20 TI - Genome mining for peptidases in heat-tolerant and mesophilic fungi and putative adaptations for thermostability JO - BMC Genomics SP - 152 VL - 19 IS - 1 AB - Peptidases (EC 3.4) consist of a large group of hydrolytic enzymes that catalyze the hydrolysis of proteins accounting for approximately 65% of the total worldwide enzyme production. Peptidases from thermophilic fungi have adaptations to high temperature that makes them adequate for biotechnological application. In the present study, we profiled the genomes of heat-tolerant fungi and phylogenetically related mesophilic species for genes encoding for peptidases and their putative adaptations for thermostability. SN - 1471-2164 UR - https://doi.org/10.1186/s12864-018-4549-5 DO - 10.1186/s12864-018-4549-5 ID - de Oliveira2018 ER -