Table 3 Gene ontology enrichment analysis
Ontology | Gene ontology class | p-value |
|---|---|---|
Cellular component | 1. MHC protein complex | 1.32E-06 |
2. Integral component of lumenal side of ER membrane | 1.52E-06 | |
3. Lumenal side of ER membrane | 1.52E-06 | |
4. ER to Golgi transport vesicle membrane | 2.09E-05 | |
5. ER to Golgi transport vesicle | 7.44E-05 | |
Molecular function | 1. Peptide antigen binding | 1.50E-03 |
2. TAP binding | 1.58E-02 | |
3. MHC class II receptor activity | 3.91E-02 | |
4. Antigen binding | 4.95E-01 | |
5. Peptide binding | 6.13E-01 | |
Biological process | 1. Interferon-gamma-mediated signaling pathway | 3.49E-04 |
2. Cellular response to interferon-gamma | 3.30E-03 | |
3. Response to interferon-gamma | 6.28E-03 | |
4. Antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent | 9.23E-03 | |
5. Antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway | 9.23E-03 |