From: The deregulated microRNAome contributes to the cellular response to aneuploidy
Cell line | HCT116 5/4 | RPE1 5/3 12/3 | RPE1* 21/3 | HCT116 8/3 c7 |
---|---|---|---|---|
Deregulated mRNAs | 3342 | 2484 | 788 | 250 |
Deregulated miRNAs (DEmiRNA) | 74 | 74 | 23 | 44 |
ALL TARBASE TARGETS | ||||
Number of targets of DEmiRNAs | ||||
Total miRNA-target interactions | 9111 | 6487 | 6036 | 965 |
Unique interactions | 6644 | 4605 | 5078 | 877 |
% of those deregulated on mRNA level | 38.3% (1280) | 24.3% (604) | 27.2% (214) | 4.8% (12) |
Targets of DEmiRNAs with inverse expression: | ||||
Total interactions | 904 | 406 | 142 | 7 |
Unique interactions | 729 | 345 | 127 | 7 |
TARBASE TARGETS WITH STRONG EVIDENCE | ||||
Number of targets of DEmiRNAs | ||||
Total miRNA-target interactions | 729 | 546 | 496 | 213 |
Unique interactions | 520 | 417 | 431 | 193 |
% of those deregulated on mRNA level | 4.0% (133) | 2.7% (68) | 4.0% (20) | 2.8% (6) |
Targets of DEmiRNAs with inverse expression: | ||||
Total interactions | 154 | 54 | 20 | 3 |
Unique interactions | 93 | 40 | 13 | 3 |