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Table 1 RFX1–8 expression data and novel transcripts

From: Characterization of the human RFX transcription factor family by regulatory and target gene analysis

Gene (chromosome)

TSS

Matched

Ensemble transcript

Tissue profile summary

Expression

Highest in

RFX1 (chr19)

pA@RFX1

ENST00000254325

Broad

Cerebellum (brain)

pB@RFX1

ENST00000254325

pC@RFX1*

Novel transcript*

Specific

Testis

RFX2 (chr19)

pA@RFX2

ENST00000303657

Broad

Uterus

pB@RFX2

ENST00000303657

Testis

pC@RFX2

ENST00000303657

Medulla oblongata (brain)

RFX3 (chr9)

pA@RFX3

ENST00000382004

Broad

Cerebellum (brain)

pB@RFX3

ENST00000382004

Lung, fetal

pC@RFX3*

Novel transcript*

Cerebellum (brain)

pD@RFX3

ENST00000382004

Lung, fetal

pE@RFX3*

Novel transcript*

Specific

Testis

RFX4 (chr12)

pA@RFX4

ENST00000392842

Specific

Spinal cord

pB@RFX4

ENST00000229387

Specific

Testis

pC@RFX4

ENST00000357881

RFX5 (chr1)

pA@RFX5

ENST00000290524

Broad

Blood (immune system)

pB@RFX5

ENST00000290524

Tonsil (immune system)

pC@RFX5*

Novel transcript*

Brain, fetal

pD@RFX5

Novel transcript

Duodenum, fetal (GI)

RFX6 (chr6)

pA@RFX6

ENST00000332958

Specific

Duodenum, fetal (GI)

pB@RFX6

ENST00000332958

pC@RFX6

ENST00000332958

RFX7 (chr15)

pA@RFX7*

Novel transcript*

Broad

Cerebellum (brain)

pB@RFX7

ENST00000559447

pC@RFX7*

Novel transcript*

pD@RFX7

Novel transcript

RFX8 (chr2)

pA@RFX8*

Novel transcript*

Lowly expressed (TPM < 5)

Thymus (immune system)

pB@RFX8

ENST00000428343

Medial frontal gyrus (brain)

pC@RFX8

Novel transcript

Noise (TPM < 1)

Heart

pD@RFX8

Novel transcript

Breast

pE@RFX8

Novel transcript

Rectum, fetal

  1. Thirty TSS locations from eight human RFX genes and their respective tissue profile summaries are presented (cf. Methods; GI = gastrointestinal tract). For an expanded summary and the analysis of functional domains, see Tables S1 and S2 in Additional file 3, respectively. Novel transcripts are marked in bold and those selected for experimental validation are marked with an asterisk. For RT-PCR verified sequences of novel transcripts, see Table S9 in Additional file 3