Molecular mechanisms of an antimicrobial peptide piscidin (Lc-pis) in a parasitic protozoan, Cryptocaryon irritans

Table 3 The top 20 most up-regulated and down-regulated genes between theronts and trophonts. The rich factor refers to the ratio of the number of differentially expressed genes in the pathway and the number of all genes in the pathway

Pathway_term	Rich_factor	q-value	Gene_Number
Ribosome	0.142451	4.84E-13	351
Vibrio cholerae infection	0.143921	0.075845	58
Prion diseases	0.170000	0.075845	34
Pathogenic Escherichia coli infection	0.165877	0.075845	35
Cocaine addiction	0.194444	0.097259	21
Phagosome	0.127301	0.097259	83
mTOR signaling pathway	0.134518	0.191181	53
Oxidative phosphorylation	0.116246	0.521090	83
Parkinson”‘“s disease	0.115033	0.521090	88
Ribosome biogenesis in eukaryotes	0.119772	0.561419	63
Steroid biosynthesis	0.172840	0.634712	14
Non-alcoholic fatty liver disease (NAFLD)	0.115702	0.642030	70
Hedgehog signaling pathway	0.135266	0.696605	28
Ovarian steroidogenesis	0.153846	0.792778	16
Vasopressin-regulated water reabsorption	0.125000	0.792778	36
Thyroid hormone synthesis	0.122517	0.794620	37
Protein export	0.138889	0.794620	20
Plant-pathogen interaction	0.118457	0.794620	43
Apoptosis	0.123134	0.794620	33
Toxoplasmosis	0.113131	0.794620	56

ISSN: 1471-2164