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Fig. 4 | BMC Genomics

Fig. 4

From: Evolutionary analysis of mitochondrially encoded proteins of toad-headed lizards, Phrynocephalus, along an altitudinal gradient

Fig. 4

The three dimensional structure of Complex I showing the locations of amino acids under selection as determined by predictive models for individual Phrynocephalus ND subunits. Residues marked as blue circles are the selected residues within the reference crystal structure (PDB ID 3RKO). Diagrams of residue side chains are given for each. Each ND subunit is coloured individually, protein names correspond to the protein subunits in Complex I. Blue stars indicate the two residues that show significant co-evolutionary relationship with key residues (in grey sphere) in the chain of proton translocation

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