1000 human genomes carry widespread signatures of GC biased gene conversion

BMC Genomics

Table 1 Distribution of computational segments and putative gene conversion events in all autosomes

Chromo-some	# of Segments	Rare haplotype count = 1				Rare haplotype count <= 5
Chromo-some	# of Segments	AT → GC cases	GC → AT cases	No Base Change cases	Total cases	AT → GC cases	GC → AT cases	No Base Change cases	Total cases
1	4359	1964	1677	637	4278	8973	8200	3181	20,354
2	4660	2318	1921	760	4999	10,514	8928	3605	23,047
3	4048	1977	1640	632	4249	8785	7715	3196	19,696
4	4191	1945	1891	722	4558	9034	8442	3373	20,849
5	3687	1786	1513	629	3928	7842	7190	3052	18,084
6	3869	1791	1614	629	4034	8516	7835	2975	19,326
7	2838	1361	1227	492	3080	6133	5431	2311	13,875
8	3179	1631	1287	560	3478	7124	6170	2691	15,985
9	2389	1163	963	420	2546	4898	4253	1814	10,965
10	2830	1311	1112	423	2846	5897	5283	1997	13,177
11	2838	1352	1196	479	3027	5943	5444	2302	13,689
12	2676	1150	1035	391	2576	5475	4978	1953	12,406
13	2135	948	772	282	2002	4334	4000	1518	9852
14	1852	862	757	277	1896	3781	3368	1422	8571
15	1647	789	627	251	1667	3362	2822	1176	7360
16	1723	794	629	367	1790	3440	2787	1501	7728
17	1540	713	606	201	1520	3144	2709	1027	6880
18	1629	720	603	226	1549	3057	2728	1110	6895
19	1334	662	511	196	1369	2678	2314	868	5860
20	1272	559	449	146	1154	2350	2083	785	5218
21	840	384	326	121	831	1620	1411	574	3605
22	792	403	290	125	818	1643	1321	523	3487

The first two columns of Table 1 lists the number of computationally generated segments in different human autosomes. The next four columns describe number of AT to GC, number of GC to AT, number of ‘No Base Change’ and total mismatch repair cases respectively in all autosomes when only single rare haplotype occurrence in the 1092 genomes was considered. The last four columns present number of AT to GC cases, number of GC to AT cases, number of ‘No Base Change’ cases and total mismatch repair cases respectively in all autosomes when rare haplotype occurrence <= 5 in the 1092 genomes was considered

ISSN: 1471-2164