Skip to main content
Fig. 2 | BMC Genomics

Fig. 2

From: Defense against territorial intrusion is associated with DNA methylation changes in the honey bee brain

Fig. 2

Gene expression changes in response to intruder are marked by both early and late epigenetic differences. Gene expression differences between aggressive and control bees that arise 120 min after interaction with an intruder are often marked with differences in DNA methylation. There were 140 genes that had differential methylation both before and after gene expression changes occurred. For both (a) and (b), the top panel depicts boxplots of DNA methylation levels at both time points for aggressive and control bees. Asterisks indicate significant differences between aggressive and control bees within time points. Note that different sets of CpGs have significant differences at different time points, thus marking gene before and after gene expression change at 120 min with distinct CpGs. The bottom panel shows the differentially expressed gene and the location of the CpGs within the gene body. (c) Summary of overlap between 120-min DEGs and suggestive CpG’s. Both 5-min and 120-min suggestive CpGs have significant overlaps with120-minute DEGs, with a high degree of co-localization within a subset of genes. (d) GO enrichments for genes both differentially expressed and differentially methylated in response to intruder exposure

Back to article page