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Table 1 Summary of the sequence data of CGS transcriptome, number of virus gene with paired reads, and significantly enriched immune pathways from different treatments

From: Divergent transcriptomic responses underlying the ranaviruses-amphibian interaction processes on interspecies infection of Chinese giant salamander

Sample treatment CGS Number of virus genes with paired reads Significantly enriched immune pathways
Number of cleaned reads Number of Unigenes Number of DEGs
(compared to Control)
HCL TLR CCC APP NKC III RIG
1 Control 51,382,240 70,307          
2 Control 56,930,824 74,222        
3 Control 48,322,278 72,107        
  Control-total 156,635,342 92,642          
4 RGV-1d 54,425,646 72,588 557 (501↑, 56↓) 95 + +      
5 RGV-1d 58,594,944 75,232
6 RGV-1d 63,939,152 76,704
  RGV-1d-total 176,959,742 97,513          
7 RGV-7d 49,123,866 67,404 1852 (933↑, 919↓) 16 +    + +   
8 RGV-7d 52,736,612 73,301
9 RGV-7d 50,018,476 70,402
  RGV-7d-total 151,878,954 92,198          
10 ADRV-1d 56,001,870 68,499 1013 (763↑, 250↓) 29 + + + +    
11 ADRV-1d 47,824,738 67,468
12 ADRV-1d 66,289,046 69,480
  ADRV-1d-total 170,115,654 87,131          
13 ADRV-7d 59,093,102 67,797 3880 (2694↑, 1186↓) 93 + + +   + + +
14 ADRV-7d 56,800,712 77,340
15 ADRV-7d 49,374,622 73,957
  ADRV-7d-total 165,268,436 95,375          
  Total 820,858,128 128,533          
  1. HCL hematopoietic cell lineage, TLR toll-like receptor signaling pathway, CCC complement and coagulation cascades, APP antigen processing and presentation, NKC natural killer cell mediated cytotoxicity, III intestinal immune network for IgA production, RIG rIG-I-like receptor signaling pathway
  2. “↑” and “↓” indicates up- and down-regulate respectively. “+” means significantly enriched