RNA-Seq analysis validates the use of culture-derived Trypanosoma brucei and provides new markers for mammalian and insect life-cycle stages

Table 1 Genes implicated in inositol metabolism are up-regulated in stumpy forms

Gene ID	Description	St/Sl	St/Ea	Reference
Tb927.10.3890	Phosphatidylinositol-4-phosphate 5-kinase, putative (PIP5KII-alpha)	1.9	1.36
Tb927.11.15330	Phosphatidylinositol 3-kinase catalytic subunit, putative	1.97	1.46
Tb927.10.7110	Inositol-3-phosphate synthase	1.98	1.63
Tb927.2.2260	Phosphatidylinositol kinase related protein, putative	2.53	0.78
Tb927.10.8420	Target of rapamycin kinase 1 (TOR1)	1.83	1.04
Tb927.4.420	Phosphatidylinositol 3-kinase (TOR2)	2.61	1.82	[33]
Tb927.4.800	Target of rapamycin kinase 3, putative (TOR3)	1.91	0.99	[33]
Tb927.1.1930	Phosphatidylinositol 3-kinase, putative (TOR4)	3.7	1.64
Tb927.8.2770	Inositol 1,4,5-trisphosphate receptor (IP3R)	2.63	0.66	[30]
Tb927.7.4400	Inositol hexakisphosphate kinase	3.11	1.73	[31]
Tb927.8.3410	Inositol hexakisphosphate, putative	3.83	2.39
Tb927.7.960	CMGC/SRPK protein kinase, putative (inositol pyrophosphate biosynthesis)	2.44	0.99	[32]

St/Sl fold change stumpy/slender forms, St/Ea fold change stumpy/early procyclic forms

ISSN: 1471-2164