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Table 3 Statistically significant GSEA summary results in liver of males and females (FDR < 0.05)

From: Gene co-expression networks in liver and muscle transcriptome reveal sex-specific gene expression in lambs fed with a mix of essential oils

  KEGG pathway Size ES NES FDR
Males Protein Export 15 −0.60 0.000 0.001
Proteasome 33 −0.37 0.000 0.002
Antigen Processing and Presentation 20 −0.43 0.000 0.006
Rna Degradation 16 −0.38 0.012 0.116
Aminoacyl Trna Biosynthesis 19 −0.30 0.031 0.310
Ppar Signaling Pathway 29 0.43 0.000 0.000
Glycolysis Gluconeogenesis 21 0.48 0.000 0.001
Drug Metabolism Cytochrome P450 20 0.44 0.000 0.006
Glycine Serine and Threonine Metabolism 22 0.38 0.002 0.034
Peroxisome 48 0.26 0.000 0.028
Retinol Metabolism 16 0.43 0.006 0.031
Citrate Cycle Tca Cycle 20 0.37 0.002 0.037
Metabolism Of Xenobiotics By Cytochrome P450 17 0.41 0.006 0.033
Females Cytokine Cytokine Receptor Interaction 94 −0.21 0.000 0.019
Pathogenic Escherichia coli Infection 35 0.40 0.000 0.001
Proteasome 34 0.37 0.000 0.003
Amino Sugar and Nucleotide Sugar Metabolism 36 0.33 0.000 0.009
Glycolysis Gluconeogenesis 33 0.34 0.000 0.017
Ecm Receptor Interaction 55 0.25 0.000 0.022
Cysteine and Methionine Metabolism 25 0.35 0.004 0.037
Protein Export 19 0.39 0.002 0.047
  1. Size = Number of genes. ES Enrichment score. ES represents the overepresentation degree of top and bottom genes included in ranked list based on log2FoldChange of DE genes included. NES Normalized enrichment score