From: Comparison of normalization methods for the analysis of metagenomic gene abundance data
Methods | Human gut I | Human gut II | Marine | |||
---|---|---|---|---|---|---|
 | B | U | B | U | B | U |
TMM | 0.28 | 0.25 | 0.21 | 0.18 | 0.40 | 0.36 |
RLE | 0.28 | 0.25 | 0.20 | 0.17 | 0.40 | 0.36 |
CSS | 0.20 | 0.15 | 0.18 | 0.12 | 0.32 | 0.28 |
RCSS | 0.28 | 0.27 | 0.21 | 0.18 | 0.39 | 0.33 |
Quantile-quantile | 0.28 | 0.24 | 0.16 | 0.13 | 0.37 | 0.29 |
Upper quartile | 0.29 | 0.24 | 0.21 | 0.18 | 0.40 | 0.29 |
Median | 0.22 | 0.17 | 0.18 | 0.12 | 0.35 | 0.28 |
Total count | 0.29 | 0.26 | 0.21 | 0.17 | 0.39 | 0.33 |
Rarefying | 0.29 | 0.26 | 0.13 | 0.10 | 0.40 | 0.33 |