Table 2 The top 10 up- and down-regulated genes in bovine granulosa cells sampled from cows after a long (7-day) vs conventional (4-day) FSH superstimulatory treatment protocol (3 largest follicles pooled)
Genes | Description | P value | Fold change |
|---|---|---|---|
Up-Regulated | |||
 PTX3 | Pentraxin 3 | 3.7 × 10−13 | 5.904 |
 VNN3 | Vanin 3 | 3.3 × 10−11 | 5.281 |
 POSTN | Pcriostin, Osteoblast specific factor | 1.4 × 10−07 | 4.241 |
 PTGS2 | Prostaglandin cndopcroxidc synthase 2 | 1.5 × 10−07 | 4.182 |
 GRIA3 | Glutamate receptor, ionotropic, AMPA3 | 8.4 × 10− 07 | 4.175 |
 RGS2 | Regulator of G protein signaling 2 | 2.9 × 10−06 | 3.702 |
 GFRA1 | GDNF family receptor alpha I | 7.5 × 10−05 | 3.679 |
 PLA2G4A | Phospholipase A2 group Iva (cytosolic, Ca dependent) | 4.4 × 10−07 | 3.605 |
 CRISPLD2 | Cysteine rich secretory protein LCCL domain containing 2 | 2.9 × 10− 05 | 3.604 |
 GIMAP4 | GTPase IMAP family member 4 | 9.0 × 10−12 | 3.545 |
Down-Regulated | |||
 INHBA | Inhibin beta A | 2.0 × 10−07 | −3.978 |
 LRP8 | Low density lipoprotein receptor-related protein 8 | 1.4 × 10−07 | −3.784 |
 CCND2 | Cyclin D2 | 5.9 × 10−09 | − 3.437 |
 SRGN | Serglycin | 1.2 × 10−05 | −3.055 |
 BEX2 | Brain expressed X-linkcd 2 | 3.3 × 10−07 | −3.055 |
 INHBB | Inhibin beta B | 2.9 × 10−07 | −3.031 |