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Table 2 The top 10 up- and down-regulated genes in bovine granulosa cells sampled from cows after a long (7-day) vs conventional (4-day) FSH superstimulatory treatment protocol (3 largest follicles pooled)

From: Transcriptome analysis of granulosa cells after conventional vs long FSH-induced superstimulation in cattle

Genes Description P value Fold change
Up-Regulated
 PTX3 Pentraxin 3 3.7 × 10−13 5.904
 VNN3 Vanin 3 3.3 × 10−11 5.281
 POSTN Pcriostin, Osteoblast specific factor 1.4 × 10−07 4.241
 PTGS2 Prostaglandin cndopcroxidc synthase 2 1.5 × 10−07 4.182
 GRIA3 Glutamate receptor, ionotropic, AMPA3 8.4 × 10− 07 4.175
 RGS2 Regulator of G protein signaling 2 2.9 × 10−06 3.702
 GFRA1 GDNF family receptor alpha I 7.5 × 10−05 3.679
 PLA2G4A Phospholipase A2 group Iva (cytosolic, Ca dependent) 4.4 × 10−07 3.605
 CRISPLD2 Cysteine rich secretory protein LCCL domain containing 2 2.9 × 10− 05 3.604
 GIMAP4 GTPase IMAP family member 4 9.0 × 10−12 3.545
Down-Regulated
 INHBA Inhibin beta A 2.0 × 10−07 −3.978
 LRP8 Low density lipoprotein receptor-related protein 8 1.4 × 10−07 −3.784
 CCND2 Cyclin D2 5.9 × 10−09 − 3.437
 SRGN Serglycin 1.2 × 10−05 −3.055
 BEX2 Brain expressed X-linkcd 2 3.3 × 10−07 −3.055
 INHBB Inhibin beta B 2.9 × 10−07 −3.031