Table 2 Top differentially methylated CpGs (associated with maternal smoking after correction for multiple testing)
From: Impact on birth weight of maternal smoking throughout pregnancy mediated by DNA methylation
Name | Chromosome | Chromosomal position | UCSC RefGene name | UCSC RefGene group | Relation_to_UCSC CpG_Island | Differencea | P-value | FDRb |
|---|---|---|---|---|---|---|---|---|
cg04865726 | 1 | 1365911 | S_Shelf | 0,033 | 5,39E-05 | 1,65E-02 | ||
cg09662411 | 1 | 92946132 | GFI1 | Body | Island | -0,115 | 3,69E-07 | 3,98E-04 |
cg06338710 | 1 | 92946187 | GFI1 | Body | Island | -0,099 | 2,26E-05 | 8,94E-03 |
cg18146737 | 1 | 92946700 | GFI1 | Body | Island | -0,128 | 7,51E-07 | 5,19E-04 |
cg12876356 | 1 | 92946825 | GFI1 | Body | Island | -0,178 | 1,07E-06 | 6,55E-04 |
cg18316974 | 1 | 92947035 | GFI1 | Body | Island | -0,057 | 4,32E-07 | 3,98E-04 |
cg09935388 | 1 | 92947588 | GFI1 | Body | Island | -0,194 | 2,72E-09 | 7,52E-06 |
cg14179389 | 1 | 92947961 | GFI1 | Body | Island | -0,061 | 5,07E-08 | 9,34E-05 |
cg11641006 | 2 | 235213874 | 0,078 | 1,40E-05 | 6,45E-03 | |||
cg23067299 | 5 | 323907 | AHRR | Body | S_Shore | 0,031 | 7,71E-05 | 2,17E-02 |
cg23916896 | 5 | 368804 | AHRR | Body | N_Shore | -0,025 | 2,12E-04 | 4,22E-02 |
cg11902777 | 5 | 368843 | AHRR | Body | N_Shore | -0,005 | 1,99E-04 | 4,22E-02 |
cg05575921 | 5 | 373378 | AHRR | Body | N_Shore | -0,075 | 1,24E-15 | 6,85E-12 |
cg21161138 | 5 | 399360 | AHRR | Body | -0,043 | 2,63E-05 | 9,68E-03 | |
cg25325512 | 6 | 37142220 | PIM1 | 3'UTR | S_Shelf | -0,062 | 1,52E-04 | 3,65E-02 |
cg23594693 | 6 | 41703970 | TFEB | 5'UTR;TSS1500;1stExon | S_Shore | 0,027 | 1,32E-04 | 3,46E-02 |
cg02227813 | 6 | 130524018 | SAMD3; SAMD3 | Body | 0,040 | 7,86E-05 | 2,17E-02 | |
cg07249149 | 7 | 1035363 | -0,051 | 1,77E-04 | 3,91E-02 | |||
cg19089201 | 7 | 45002287 | MYO1G | 3'UTR | Island | 0,028 | 1,29E-05 | 6,45E-03 |
cg22132788 | 7 | 45002486 | MYO1G | Body | Island | 0,019 | 2,14E-04 | 4,22E-02 |
cg04180046 | 7 | 45002736 | MYO1G | Body | Island | 0,063 | 5,31E-07 | 4,19E-04 |
cg12803068 | 7 | 45002919 | MYO1G | Body | S_Shore | 0,109 | 1,56E-05 | 6,64E-03 |
cg25949550 | 7 | 145814306 | CNTNAP2 | Body | S_Shore | -0,009 | 8,90E-08 | 1,23E-04 |
cg15578140 | 7 | 147718109 | MIR548F3;CNTNAP2 | Body | 0,054 | 8,01E-06 | 4,43E-03 | |
cg11813497 | 10 | 14372879 | FRMD4A | TSS200 | 0,043 | 1,39E-04 | 3,49E-02 | |
cg26033520 | 10 | 74004071 | -0,026 | 2,63E-04 | 4,84E-02 | |||
cg08699196 | 12 | 53591398 | ITGB7 | Body | Island | 0,028 | 2,50E-04 | 4,77E-02 |
cg05549655 | 15 | 75019143 | CYP1A1 | TSS1500 | Island | 0,021 | 4,76E-05 | 1,56E-02 |
cg13859324 | 17 | 33474692 | UNC45B | TSS200;TSS200 | 0,032 | 4,79E-05 | 1,56E-02 | |
cg11043990 | 17 | 74235759 | RNF157 | Body | Island | 0,017 | 1,60E-04 | 3,69E-02 |