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Table 2 Top differentially methylated CpGs (associated with maternal smoking after correction for multiple testing)

From: Impact on birth weight of maternal smoking throughout pregnancy mediated by DNA methylation

Name Chromosome Chromosomal position UCSC RefGene name UCSC RefGene group Relation_to_UCSC CpG_Island Differencea P-value FDRb
cg04865726 1 1365911    S_Shelf 0,033 5,39E-05 1,65E-02
cg09662411 1 92946132 GFI1 Body Island -0,115 3,69E-07 3,98E-04
cg06338710 1 92946187 GFI1 Body Island -0,099 2,26E-05 8,94E-03
cg18146737 1 92946700 GFI1 Body Island -0,128 7,51E-07 5,19E-04
cg12876356 1 92946825 GFI1 Body Island -0,178 1,07E-06 6,55E-04
cg18316974 1 92947035 GFI1 Body Island -0,057 4,32E-07 3,98E-04
cg09935388 1 92947588 GFI1 Body Island -0,194 2,72E-09 7,52E-06
cg14179389 1 92947961 GFI1 Body Island -0,061 5,07E-08 9,34E-05
cg11641006 2 235213874     0,078 1,40E-05 6,45E-03
cg23067299 5 323907 AHRR Body S_Shore 0,031 7,71E-05 2,17E-02
cg23916896 5 368804 AHRR Body N_Shore -0,025 2,12E-04 4,22E-02
cg11902777 5 368843 AHRR Body N_Shore -0,005 1,99E-04 4,22E-02
cg05575921 5 373378 AHRR Body N_Shore -0,075 1,24E-15 6,85E-12
cg21161138 5 399360 AHRR Body   -0,043 2,63E-05 9,68E-03
cg25325512 6 37142220 PIM1 3'UTR S_Shelf -0,062 1,52E-04 3,65E-02
cg23594693 6 41703970 TFEB 5'UTR;TSS1500;1stExon S_Shore 0,027 1,32E-04 3,46E-02
cg02227813 6 130524018 SAMD3; SAMD3 Body   0,040 7,86E-05 2,17E-02
cg07249149 7 1035363     -0,051 1,77E-04 3,91E-02
cg19089201 7 45002287 MYO1G 3'UTR Island 0,028 1,29E-05 6,45E-03
cg22132788 7 45002486 MYO1G Body Island 0,019 2,14E-04 4,22E-02
cg04180046 7 45002736 MYO1G Body Island 0,063 5,31E-07 4,19E-04
cg12803068 7 45002919 MYO1G Body S_Shore 0,109 1,56E-05 6,64E-03
cg25949550 7 145814306 CNTNAP2 Body S_Shore -0,009 8,90E-08 1,23E-04
cg15578140 7 147718109 MIR548F3;CNTNAP2 Body   0,054 8,01E-06 4,43E-03
cg11813497 10 14372879 FRMD4A TSS200   0,043 1,39E-04 3,49E-02
cg26033520 10 74004071     -0,026 2,63E-04 4,84E-02
cg08699196 12 53591398 ITGB7 Body Island 0,028 2,50E-04 4,77E-02
cg05549655 15 75019143 CYP1A1 TSS1500 Island 0,021 4,76E-05 1,56E-02
cg13859324 17 33474692 UNC45B TSS200;TSS200   0,032 4,79E-05 1,56E-02
cg11043990 17 74235759 RNF157 Body Island 0,017 1,60E-04 3,69E-02
  1. aBeta-Value Mean-Differences between Smoking vs Non-Smoking group
  2. bFalse discovery rate