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Fig. 3 | BMC Genomics

Fig. 3

From: Identification of new loci involved in the host susceptibility to Salmonella Typhimurium in collaborative cross mice

Fig. 3

Founder contributions and haplotype around Stsl1 QTL on Chr 8. (a) Genome scan magnification for Stsl1 QTL region (0–30 Mb on Chr 8). The mouse genome location is on the X-axis and significance (−log10(P)) values on the Y-axis, with genome-wide thresholds of association at E < 0.5, E < 0.1 and E < 0.05 levels indicated respectively by the gray, orange and red lines. Peak location (maximum value of –log10(P)) is marked by a star. (b) Founder contributions in the same magnified region. The peak location is marked by a star. Each of the 8 founders is in a different color. The mouse genome location is on the X-axis and Y-axis shows the founder estimated effect on splenic bacterial load after S. Typhimurium infection. (c) Founder contributions at Stsl1 QTL peak (12.5 Mb). X-axis shows the different founder strains. Y-axis shows the estimated founder effect. Stsl1 QTL is caused by contrast between 129S1SvlmJ, CAST/EiJ (lower values) and PWK/PhJ (higher values)

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