Fig. 3From: Identification of new loci involved in the host susceptibility to Salmonella Typhimurium in collaborative cross miceFounder contributions and haplotype around Stsl1 QTL on Chr 8. (a) Genome scan magnification for Stsl1 QTL region (0–30 Mb on Chr 8). The mouse genome location is on the X-axis and significance (−log10(P)) values on the Y-axis, with genome-wide thresholds of association at E < 0.5, E < 0.1 and E < 0.05 levels indicated respectively by the gray, orange and red lines. Peak location (maximum value of –log10(P)) is marked by a star. (b) Founder contributions in the same magnified region. The peak location is marked by a star. Each of the 8 founders is in a different color. The mouse genome location is on the X-axis and Y-axis shows the founder estimated effect on splenic bacterial load after S. Typhimurium infection. (c) Founder contributions at Stsl1 QTL peak (12.5 Mb). X-axis shows the different founder strains. Y-axis shows the estimated founder effect. Stsl1 QTL is caused by contrast between 129S1SvlmJ, CAST/EiJ (lower values) and PWK/PhJ (higher values)Back to article page