Fig. 4From: Identification of new loci involved in the host susceptibility to Salmonella Typhimurium in collaborative cross miceFounder contributions and haplotype around Stsl2 QTL on Chr 10. (a) Genome scan magnification for Stsl2 QTL region (35–65 Mb on Chr 10). The mouse genome location is on the X-axis and significance (−log10(P)) values on the Y-axis, with genome-wide thresholds of association at E < 0.5, E < 0.1 and E < 0.05 levels indicated respectively by the gray, orange and red lines. Peak location (maximum value of –log10(P)) is marked by a star. (b) Founder contributions in the same magnified region. The peak location is marked by a star. Each of the 8 founders is in a different color. The mouse genome location is on the X-axis and Y-axis shows the founder estimated effect on splenic bacterial load after S. Typhimurium infection. (c) Founder contributions at Stsl2 QTL peak (52.3 Mb). X-axis shows the different founder strains. Y-axis shows the estimated founder effect. Stsl2 QTL is caused by contrast between B6, PWK/PhJ (lower values) and NZO/HiLtJ (higher values)Back to article page