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Fig. 4 | BMC Genomics

Fig. 4

From: Identification of new loci involved in the host susceptibility to Salmonella Typhimurium in collaborative cross mice

Fig. 4

Founder contributions and haplotype around Stsl2 QTL on Chr 10. (a) Genome scan magnification for Stsl2 QTL region (35–65 Mb on Chr 10). The mouse genome location is on the X-axis and significance (−log10(P)) values on the Y-axis, with genome-wide thresholds of association at E < 0.5, E < 0.1 and E < 0.05 levels indicated respectively by the gray, orange and red lines. Peak location (maximum value of –log10(P)) is marked by a star. (b) Founder contributions in the same magnified region. The peak location is marked by a star. Each of the 8 founders is in a different color. The mouse genome location is on the X-axis and Y-axis shows the founder estimated effect on splenic bacterial load after S. Typhimurium infection. (c) Founder contributions at Stsl2 QTL peak (52.3 Mb). X-axis shows the different founder strains. Y-axis shows the estimated founder effect. Stsl2 QTL is caused by contrast between B6, PWK/PhJ (lower values) and NZO/HiLtJ (higher values)

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