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Fig. 3 | BMC Genomics

Fig. 3

From: Complex evolution of the GSTM gene family involves sharing of GSTM1 deletion polymorphism in humans and chimpanzees

Fig. 3

Maximum likelihood trees of the human and chimpanzee segmental duplications. a We divided the segmental duplication(s) into three regions: region 1 (0-1000b), region 2 (4001-7500b), and region 3 (12000b-) based on the boundaries we predicted. Then we reconstructed maximum-likelihood trees for (b) region 1, (c) region 2, and (d) region 3. We broke our analyse into these three regions to avoid any complications due to gene conversions, which we depicted by transparent light blue boxes. The input was human SD1 and SD2 from the reference genome, chimpanzee SD1 and SD2 from the reference genome, seven (three Asian, two European, two African) human fused SDs and seven chimpanzee fused SDs which we sequenced. Human and chimpanzee fused SDs are highlighted with blue color. Bootstrap values were described in the roots of the branches. These analyses support the recurrent segmental duplication fusion events (or in other words deletions) in human and chimpanzee lineages

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