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Table 1 Percentages of isomiRs (# of the isomiRs showing the indicated modification / # of total reads) of the miR-34 family activated by p53

From: Robust Sub-nanomolar Library Preparation for High Throughput Next Generation Sequencing

  5′ modifications 3′ modifications nucleotide substitution
  Illumina sub-nanomolar Illumina sub-nanomolar Illumina sub-nanomolar
hsa-miR-34a-5p 4.2% 3.2% 58.3% 58.0% 9.6% 9.8%
hsa-miR-34a-3p ~ ~ ~ ~ ~ ~
hsa-miR-34b-5p 95.1% 96.3% 91.8% 92.6% 6.6% 7.4%
hsa-miR-34b-3p 73.4% 66.7% 98.7% 100.0% 7.6% 8.3%
hsa-miR-34c-5p 0.9% 1.4% 6.1% 5.2% 2.6% 2.3%
hsa-miR-34c-3p ~ ~ ~ ~ ~ ~
  1. ~: # of -3p reads much lower than # of -5p reads to show reliable ratios