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Table 2 Functional gene categories showing significant enrichment for CNVs

From: Gene copy number variation in natural populations of Plasmodium falciparum in Eastern Africa

Functional gene set No. of genes in CNVs Total no. of genes in gene set Nominal Adjusted
P-valuea P-valueb
Deletions
Exported proteins - PHISTs 8 48 < 0.001 < 0.001
Characteristics of Plasmodium falciparum export proteins that remodel infected erythrocyte 5 35 < 0.001 0.043
Glycolysis 4 27 0.001 0.10
Exported proteins - Unique 6 72 0.0025 0.10
Utilization of phospholipids 4 40 0.005 0.26
Amplifications
Rab and other proteins involved in intracellular traffic 3 14 0.009 1
RNA binding genes 12 173 0.01 1
  1. aBy hypergeometric test without adjustment for testing of multiple gene sets
  2. bAdjusted for multiple-testing by the Benjamini-Hochberg method