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Fig. 7 | BMC Genomics

Fig. 7

From: Bidirectional promoters exhibit characteristic chromatin modification signature associated with transcription elongation in both sense and antisense directions

Fig. 7

Histone modification profile of bidirectional gene pair during NT2D1 EC cell differentiation. a Immunoblot for Oct4, Nanog and Sox2 for undifferentiated NT2D1 cells and 7 day RA differentiated NT2D1 cells was performed as described in ‘Methods’. After 7 days all these pluripotency factors show diminished expression indicative of differentiated cells. b Relative expression of X linked gene pair NUP62CL and PIH1D3 in undifferentiated and 7 day differentiated NT2D1 cells, normalized to GAPDH in each sample. (c, d, e, f) Relative enrichment of transcription elongation associated histone marks H3K27me1, H3K36me3, H3K79me3 and H3K4me3 in the gene pair NUP62CL and PIH1D3 upon 7 day RA mediated differentiation in NT2D1 cells

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BMC Genomics

ISSN: 1471-2164

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