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Table 3 Significant differentially expressed miRNAs between VN and VA treated groups and their predicted targets

From: Acute Hepatopancreatic Necrosis Disease (AHPND) related microRNAs in Litopenaeus vannamei infected with AHPND-causing strain of Vibrio parahemolyticus

miRNA Log2 fold change (VA/VN): miRNA transcriptome Log2 fold change (VA/VN): qPCR Targets Log2 fold change (VA/VN): target genes Annotation
bbe-miR-210-5p −2.870407322 −1.517940555 Unigene5114_All 1.060349045 p63-like transcription factor
    CL3703.Contig2_All 1.088996766 interferon alpha-inducible protein 6 isoform 1
    Unigene10324_All 1.201529506 Mucin-5 AC
    Unigene444_All 1.267391152 Mucin-2
    Unigene7288_All 2.244651906 Kazal-type serine proteinase inhibitor 4
age-miR-127 −2.588007591 −1.649872672 CL878.Contig1_All 1.4821571 lectin 3
    CL793.Contig1_All 1.830735508 C-type lectin
    Unigene711_All 1.769299871 minicollagen 1
hsa-miR-211-5p −5.092799743 −1.708656758 CL1084.Contig1_All 1.166678298 Cytochrome P450 2 L1
    Unigene23044_All 1.357617048 Mucin-19
    Unigene444_All 1.267391152 Mucin-2
    Unigene20688_All 1.711317404 nuclear transcription factor Tfp1
    CL1920.Contig3_All 1.465320468 innexin 3
tch-miR-210 −2.815959538 −1.589144004 Unigene5114_All 1.060349045 p63-like transcription factor
    CL3703.Contig2_All 1.088996766 interferon alpha-inducible protein 6 isoform 1
    Unigene10324_All 1.201529506 Mucin-5 AC
    Unigene444_All 1.267391152 Mucin-2
    Unigene7288_All 2.244651906 Kazal-type serine proteinase inhibitor 4
bmo-miR-278-5p −5.70048232 −1.446914278 Unigene10827_All 1.273096701 cytochrome P450 49a1
    Unigene6914_All 1.242144205 Mucin-5B
bta-miR-22-5p −4.70048232 −1.998632464 Unigene1405_All 1.881244868 Caspase-2
    Unigene1487_All 5.962236179 Peritrophin-1
    Unigene10827_All 1.273096701 cytochrome P450 49a1
    Unigene7890_All 1.269494038 cathepsin C
bmo-miR-9c-5p −4.802020347 −1.286244383 Unigene20818_All 1.499249658 Caspase Nc
    Unigene5907_All 12.02859678 Heat shock-related 70 kDa protein 2
    Unigene24983_All 5.12621573 High mobility group protein B3
    CL183.Contig3_All 1.643990119 Caspase-3
    Unigene21910_All 1.036005418 Cytochrome P450 3A2
dpu-miR-193 −1.274473703 −1.428703251 Unigene18431_All 2.401408994 Chymotrypsin BII
dre-miR-107b 3.106872602 1.737363291 CL1260.Contig2_All −1.153013031 Tumor protein p53-inducible protein 11
mja-miR-6489-5p 1.182514886 5.323473519 CL1919.Contig1_All −1.964210604 sarcoplasmic calcium-binding protein
    Unigene15684_All −1.244264787 suppressors of cytokine signaling-5
bta-miR-4286 4.943373869 1.464858155 CL1919.Contig1_All −1.964210604 sarcoplasmic calcium-binding protein
sha-miR-10b −1.161907157 −1.211066559 Unigene2751_All 1.405570272 Substance-K receptor
    Unigene22975_All 1.035210199 Cytokine receptor
    Unigene15784_All 1.371799521 Latrophilin-3