Fig. 4
From: Decreased testosterone levels after caponization leads to abdominal fat deposition in chickens
Enrichment of candidate pathways related to lipid metabolism and verification of related genes a The nine enriched pathways were screened based on 872 known DEGs. KEGG pathway enrichment analysis was performed using KOBAS 2.0. The enriched pathways were identified using a hypergeometric test from the R packages (P < 0.1, FDR-adjusted), and pathways with fewer than three known chicken genes were discarded. b The changes in expression of six representative genes involved in the PPAR signaling pathway. The mRNA levels of RXRG, FADS2, FABP7, and SCD, which promote lipid deposition, were significantly up-regulated in AF tissues of capons compared with sham-operated control chickens 14 wk. after caponization. FABP3 and APOA1 mRNA levels, genes involved in inhibition of lipid deposition, were significantly down-regulated. Data are means ± SEM, n = 6. *P < 0.05; **P < 0.01