Skip to main content

Table 2 The annotated differentially expressed genes enriched in the PPAR signaling pathway or ECM–receptor interaction

From: Transcriptome analysis of adipose tissues from two fat-tailed sheep breeds reveals key genes involved in fat deposition

Pathway Up-down regulation GLTPEF vs. STHPEF GLTSUF vs. STHSUF GLTTAF vs. STHTAF
PPAR signaling pathway Up LOC101114861, LOC101102230, CRABP1, PLTP, SCD5, FADS2, ACSBG2, OLR1, CPT1C, C1QTNF3, COL8A1, C1QTNF7, LOC101116326, CBLN3, LOC101114586, PDLIM2 LOC101102230, LOC101113077, SLC27A1, SLC27A5, SLC27A6, PLTP, OLR1, CPT1A, CPT1B, ANGPTL4, COL8A1, C1QTNF3, COL8A2, C1QTNF7, CBLN3, CAPRIN2, C1QTNF5, C1QTNF2, NEBL, PDLIM2, SORBS3 LOC101102230, LOC101113339, LOC101113077, SLC27A6, SLC27A5, PLTP, SCD5, LOC101102230, OLR1, CPT1B, CPT1C, CPT1A, ANGPTL4, PLIN2, FABP4, C1QTNF7, LOC101116326, CAPRIN2, C1QTNF5, LOC101114586, NEBL, PDLIM2
Down LOC101113339, FABP4, FABP5, SLC27A6, RXRG, SCD, ANGPTL4, PLIN1, PLIN5, ADIPOQ, UCP1 FABP5, CRABP2, CRABP1, SLC27A2, RXRA, SCD, FADS2, CYB5A, ACSL6, ACSL5, ACSL1, ACSBG1, PLIN2, PLIN5, PLIN3, ADIPOQ, UCP1 FABP12, CRABP2, RXRG, RXRA, SCD, FADS2, CYB5A, ACSL6, ACSL1, ACSL5, ACSL3, LOC101117914, SORBS1, UCP1
ECM-receptor interaction Up COL4A6, COL4A5, COL4A3, COL23A1, ARID5A, COL1A1, COL13A1, COL1A2, LAMB3, MEGF9, LAMA5, RELN, THSD1, ISM1, FN1, ITGA5, TNC, ANGPTL1, TNXB, TENM3, ITGA8, ITGA9, ITGA11, ZAN, FCGBP, ITGBL1, ITGB4 COL6A5, COL6A6, COL6A1, COL6A3, COL6A2, PIMREG, KRBA1, TNKS1BP1, ARID5A, EHBP1L1, AHNAK, LAMB3, LAMA2, LAMB1, RELN, THBS1, COMP, THBS2, THBS3, THBS4, THSD1, FN1, ITGA5, SDK2, ANGPTL6, ANGPTL1, TNXB, TNC, IGDCC4, ITGA8, ITGA9, ITGA11, ITGB3, ITGBL1, ITGA2, ITGA4, SPP1, PRG4, ITGB7, ITGB5 COL9A3, COL2A1, COL13A1, COL11A2, TNKS1BP1,COL6A5, COL23A1, EHBP1L1, LAMB3, LAMB1, LAMA2, RELN, THBS2, THBS1, SCARF1, TNXB, ITGA8, VWF, ITGA2, SPP1, VTN, TGB7, ITGB5
Down WFIKKN2, WAP, PIMREG, LAMB4, COMP COL24A1, GRTP1, COL11A1, LOC101117707, LAMB4, SSPO, C5H19orf70, ITGA3 COL24A1, PIMREG, GRTP1, COL5A1, COL3A1, COL5A3, COL5A2, COL11A1, COL1A2, COL1A1, LAMC2, LAMB4, LOC101117707, MEGF9, ATRN, SM1, LOC101120408, TENM4, TENM1, ITGA1, ITGA6, TGAV, ITGB8
  1. The differentially expressed genes (DE genes) were generated from comparisons, GLTPEF vs. STHPEF, GLTSUF vs. STHSUF, and GLTTAF vs. STHTAF. The PPAR signaling pathway and ECM–receptor interaction were identified through KEGG pathway analysis. “Up-down regulation” means that the genes were up- or down-regulated in STH as compared to their expression levels in GLT sheep