Table 2 The annotated differentially expressed genes enriched in the PPAR signaling pathway or ECM–receptor interaction

PPAR signaling pathway

Up

LOC101114861, LOC101102230, CRABP1, PLTP, SCD5, FADS2, ACSBG2, OLR1, CPT1C, C1QTNF3, COL8A1, C1QTNF7, LOC101116326, CBLN3, LOC101114586, PDLIM2

LOC101102230, LOC101113077, SLC27A1, SLC27A5, SLC27A6, PLTP, OLR1, CPT1A, CPT1B, ANGPTL4, COL8A1, C1QTNF3, COL8A2, C1QTNF7, CBLN3, CAPRIN2, C1QTNF5, C1QTNF2, NEBL, PDLIM2, SORBS3

LOC101102230, LOC101113339, LOC101113077, SLC27A6, SLC27A5, PLTP, SCD5, LOC101102230, OLR1, CPT1B, CPT1C, CPT1A, ANGPTL4, PLIN2, FABP4, C1QTNF7, LOC101116326, CAPRIN2, C1QTNF5, LOC101114586, NEBL, PDLIM2

Down

LOC101113339, FABP4, FABP5, SLC27A6, RXRG, SCD, ANGPTL4, PLIN1, PLIN5, ADIPOQ, UCP1

FABP5, CRABP2, CRABP1, SLC27A2, RXRA, SCD, FADS2, CYB5A, ACSL6, ACSL5, ACSL1, ACSBG1, PLIN2, PLIN5, PLIN3, ADIPOQ, UCP1

FABP12, CRABP2, RXRG, RXRA, SCD, FADS2, CYB5A, ACSL6, ACSL1, ACSL5, ACSL3, LOC101117914, SORBS1, UCP1

ECM-receptor interaction

Up

COL4A6, COL4A5, COL4A3, COL23A1, ARID5A, COL1A1, COL13A1, COL1A2, LAMB3, MEGF9, LAMA5, RELN, THSD1, ISM1, FN1, ITGA5, TNC, ANGPTL1, TNXB, TENM3, ITGA8, ITGA9, ITGA11, ZAN, FCGBP, ITGBL1, ITGB4

COL6A5, COL6A6, COL6A1, COL6A3, COL6A2, PIMREG, KRBA1, TNKS1BP1, ARID5A, EHBP1L1, AHNAK, LAMB3, LAMA2, LAMB1, RELN, THBS1, COMP, THBS2, THBS3, THBS4, THSD1, FN1, ITGA5, SDK2, ANGPTL6, ANGPTL1, TNXB, TNC, IGDCC4, ITGA8, ITGA9, ITGA11, ITGB3, ITGBL1, ITGA2, ITGA4, SPP1, PRG4, ITGB7, ITGB5

COL9A3, COL2A1, COL13A1, COL11A2, TNKS1BP1,COL6A5, COL23A1, EHBP1L1, LAMB3, LAMB1, LAMA2, RELN, THBS2, THBS1, SCARF1, TNXB, ITGA8, VWF, ITGA2, SPP1, VTN, TGB7, ITGB5

Down

WFIKKN2, WAP, PIMREG, LAMB4, COMP

COL24A1, GRTP1, COL11A1, LOC101117707, LAMB4, SSPO, C5H19orf70, ITGA3

COL24A1, PIMREG, GRTP1, COL5A1, COL3A1, COL5A3, COL5A2, COL11A1, COL1A2, COL1A1, LAMC2, LAMB4, LOC101117707, MEGF9, ATRN, SM1, LOC101120408, TENM4, TENM1, ITGA1, ITGA6, TGAV, ITGB8