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Fig. 4 | BMC Genomics

Fig. 4

From: Identification and analysis of ribosome-associated lncRNAs using ribosome profiling data

Fig. 4

Analysis of coding potential by using FLOSS, RRS, and Framescore on the HeLa dataset. a Venn diagram of putative ORFs in ribosome-associated lncRNAs evaluated by three coding filters (FLOSS, RRS, and Framescore). b Comparisons of the coding potential among CDSs (blue) and putative ORFs of ribosome-associated (red) or ribosome-free lncRNAs (green) for FLOSS, RRS, and Framescore, respectively. Based on these three coding metrics, we generated three cut-offs (the 10th percentiles represented as horizontal dashed lines) from CDSs to independently filter translation events for lncRNAs. For a coding filter of FLOSS, RRS, or Framescore, lncRNAs above the corresponding cut-off values (including the cut-off values) are identified as putatively translated lncRNAs according to this coding filter. (See Additional file 12 for the other datasets)

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