RNA-Seq Meta-analysis identifies genes in skeletal muscle associated with gain and intake across a multi-season study of crossbred beef steers

Table 4 Significant pathways for DEGs associated with the gain main effect identified using IPA

Pathway	P-value^a	DEGs in Pathway
Mitochondrial Dysfunction	0.00296	BCL2, NDUFA6, UQCRQ
Glycerol-3-phosphate shuttle	0.00672	GPD1
Glycerol degradation I	0.0101	GPD1
Death receptor signaling	0.0107	ACTC1, BCL2
VEGF signaling	0.013	ACTC1, BCL2
Oxidative phosphorylation	0.0145	NDUFA6, UQCRQ
Phosphatidylethanolamine biosynthesis II	0.0151	ETNK2
Pancreatic adenocarcinoma signaling	0.0169	BCL2, RALGDS
Gai signaling	0.0174	NPR3, RALGDS
nNOS signaling in skeletal muscle cells	0.025	SNTA1
Glutathione redox reactions I	0.0397	MGST3
NRF2-mediated oxidative stress response	0.0418	ACTC1, MGST3
ILK signaling	0.043	ACTC1, LIMS2

ISSN: 1471-2164