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Table 4 Significant pathways for DEGs associated with the gain main effect identified using IPA

From: RNA-Seq Meta-analysis identifies genes in skeletal muscle associated with gain and intake across a multi-season study of crossbred beef steers

Pathway P-valuea DEGs in Pathway
Mitochondrial Dysfunction 0.00296 BCL2, NDUFA6, UQCRQ
Glycerol-3-phosphate shuttle 0.00672 GPD1
Glycerol degradation I 0.0101 GPD1
Death receptor signaling 0.0107 ACTC1, BCL2
VEGF signaling 0.013 ACTC1, BCL2
Oxidative phosphorylation 0.0145 NDUFA6, UQCRQ
Phosphatidylethanolamine biosynthesis II 0.0151 ETNK2
Pancreatic adenocarcinoma signaling 0.0169 BCL2, RALGDS
Gai signaling 0.0174 NPR3, RALGDS
nNOS signaling in skeletal muscle cells 0.025 SNTA1
Glutathione redox reactions I 0.0397 MGST3
NRF2-mediated oxidative stress response 0.0418 ACTC1, MGST3
ILK signaling 0.043 ACTC1, LIMS2
  1. aCorrected for multiple testing using Benjamini Hochberg method