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Table 5 Significant pathways for DEGs associated with the intake main effect identified using IPA

From: RNA-Seq Meta-analysis identifies genes in skeletal muscle associated with gain and intake across a multi-season study of crossbred beef steers

Pathway

P-valuea

DEGs in Pathway

4-hydroxyproline degradation I

0.00803

HOGA1

Methylglyoxal degradation I

0.012

HAGHL

D-glucuronate degradation I

0.012

DCXR

Glycerol-3-phosphate shuttle

0.016

GPD1

Arginine degradation I (arginase pathway)

0.016

OAT

Arginine biosynthesis IV

0.0239

OAT

Proline biosynthesis II (from arginine)

0.0239

OAT

Arginine degradation VI (arginase 2 pathway)

0.0239

OAT

Glycerol degradation I

0.0239

GPD1

CNTF signaling

0.0267

CNTFR, HRAS

Citrulline biosynthesis

0.0318

OAT

PPARa/RXRa activation

0.0362

CHD5, GPD1, HRAS

  1. aCorrected for multiple testing using Benjamini Hochberg method