Table 4 Pathway enrichment analysis on differentially expressed genes between F1 and N1 group
KEGG pathway | Genes count | Percent | p value |
|---|---|---|---|
Cell adhesion molecules (CAMs) | 46 | 1.6 | 3.40E-10 |
Cytokine-cytokine receptor interaction | 60 | 2.1 | 5.80E-10 |
Neuroactive ligand-receptor interaction | 78 | 2.7 | 4.10E-08 |
Focal adhesion | 53 | 1.8 | 2.50E-05 |
Calcium signalling pathway | 47 | 1.6 | 5.50E-05 |
ECM-receptor interaction | 26 | 0.9 | 1.40E-04 |
Melanogenesis | 29 | 1 | 2.90E-04 |
TGF-beta signalling pathway | 24 | 0.8 | 1.20E-03 |
Vascular smooth muscle contraction | 29 | 1 | 2.60E-03 |
Adherens junction | 20 | 0.7 | 1.10E-02 |
Tyrosine metabolism | 11 | 0.4 | 2.20E-02 |
MAPK signalling pathway | 47 | 1.6 | 2.50E-02 |
Gap junction | 21 | 0.7 | 2.70E-02 |
Adrenergic signalling in cardiomyocytes | 29 | 1 | 2.90E-02 |
Wnt signalling pathway | 28 | 1 | 4.40E-02 |
Glycine, serine and threonine metabolism | 11 | 0.4 | 4.90E-02 |