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Table 4 Summary of differentially expressed genes related to nutrition

From: Dietary aquaculture by-product hydrolysates: impact on the transcriptomic response of the intestinal mucosa of European seabass (Dicentrarchus labrax) fed low fish meal diets

Classification/Transcript Name (best blast) Gene fold change as compared to the low fish meal diet (FM5)
FM20 FM5 + 5% TH FM5 + 5% SH FM5 + 5% MH
Digestion related
 TRINITY DN79635 c16 g28 2-phosphoxylose phosphatase 1 −1.85    
 TRINITY DN74666 c1 g3 Aminopeptidase N 1.97    2.92
 TRINITY DN74666 c0 g1 Aminopeptidase N     2.80
 TRINITY DN76691 c3 g3 Chymotrypsin-C   2.30   
 TRINITY DN66951 c0 g2 Dipeptidase 1     2.68
 TRINITY DN75551 c3 g1 Dipeptidyl peptidase 4 1.68    1.96
 TRINITY DN71008 c5 g1 Meprin A subunit alpha 1.54    
 TRINITY DN72685 c5 g4 Meprin A subunit beta 1.90    2.07
 TRINITY DN75683 c2 g1 Meprin A subunit beta 1.64 1.98   2.04
 TRINITY DN6986 c0 g1 Pepsin A   3.11 2.7 4.79
 TRINITY DN78404 c2 g1 Phospholipase B1, membrane-associated     3.61
 TRINITY DN77910 c4 g1 Phospholipase B1, membrane-associated     4.33
 TRINITY DN56338 c0 g1 Trypsinogen-like protein 3     −1.90
 TRINITY DN74387 c3 g1 Xaa-Pro aminopeptidase 2 2.26    2.61
 TRINITY DN75167 c0 g2 Xaa-Pro dipeptidase     1.72
Carbohydrate related
 TRINITY DN74193 c6 g1 2-oxoglutarate dehydrogenase, mitochondrial 1.82    
 TRINITY DN73012 c2 g2 ADP-dependent glucokinase     −2.19
 TRINITY DN77048 c0 g5 Beta-galactosidase     −2.18
 TRINITY DN77546 c2 g14 Beta-hexosaminidase subunit beta     3.15
 TRINITY DN76262 c5 g1 CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 2 6.76   5.3 6.90
 TRINITY DN76669 c2 g6 CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 4 2.40    
 TRINITY DN67442 c0 g3 Fructose-1,6-bisphosphatase 1   1.99   
 TRINITY DN79451 c1 g1 Fructose-bisphosphate aldolase B   2.05   2.17
 TRINITY DN77757 c0 g1 Glucose-6-phosphatase     2.48
 TRINITY DN78836 c3 g3 Glucose-6-phosphatase   2.99   3.71
 TRINITY DN77732 c1 g2 Lysosomal alpha-mannosidase     2.13
 TRINITY DN75851 c2 g4 Maltase-glucoamylase, intestinal 2.10 2.31   3.03
 TRINITY DN75571 c0 g1 Phosphoenolpyruvate carboxykinase, cytosolic [GTP] 1.70    2.34
 TRINITY DN66475 c0 g1 UDP-glucose 4-epimerase −2.69    −2.53
 TRINITY DN75517 c0 g1 UDP-glucose 6-dehydrogenase     −4.48
Starvation related
 TRINITY DN71986 c0 g1 Angiopoietin-related protein 4 −1.71    −2.88
 TRINITY DN65255 c0 g1 Collectrin     4.96
 TRINITY DN69741 c0 g2 DEP domain-containing mTOR-interacting protein 2.10    1.87
 TRINITY DN79325 c3 g4 Folliculin-interacting protein 1 1.69    
 TRINITY DN53239 c0 g1 Neuropeptide Y     −3.68
 TRINITY DN59469 c0 g1 Neuropeptide YY-A     −2.59
 TRINITY DN76722 c3 g1 Serine/threonine-protein kinase ULK2 2.57    
 TRINITY DN79318 c11 g9 14 kDa apolipoprotein −1.64    −2.91
 TRINITY DN79318 c11 g7 14 kDa apolipoprotein −1.79    −2.92
 TRINITY DN69453 c0 g1 Apolipoprotein A1/A4/E domain (pfam) −3.09    −7.19
 TRINITY DN71711 c0 g1 Apolipoprotein A-IV −2.02    − 2.84
 TRINITY DN70740 c0 g1 Apolipoprotein A-IV −3.28   −2.1 −5.05
 TRINITY DN79385 c0 g8 Apolipoprotein B-100   2.57   
 TRINITY DN73752 c8 g3 Apolipoprotein C-I (ApoC-1) pfam     −3.87
 TRINITY DN78962 c1 g23 Apolipoprotein C-II (pfam)     −2.29
 TRINITY DN78962 c1 g36 Apolipoprotein C-II (pfam) −1.66    −2.54
 TRINITY DN78793 c2 g9 Apolipoprotein Eb     −4.81
 TRINITY DN63420 c0 g2 Aquaporin FA-CHIP     2.00
 TRINITY DN76968 c1 g2 Asc-type amino acid transporter 1 1.70    
 TRINITY DN70677 c12 g4 ATP-binding cassette sub-family A member 1     1.98
 TRINITY DN78213 c1 g1 Chloride anion exchanger     2.74
 TRINITY DN68770 c0 g2 Chloride intracellular channel protein 4     2.01
 TRINITY DN67686 c1 g1 Chloride intracellular channel protein 5     1.77
 TRINITY DN69002 c1 g2 Large neutral amino acids transporter small subunit 4     1.96
 TRINITY DN79534 c0 g1 MLN64 N-terminal domain homolog     2.39
 TRINITY DN75016 c2 g2 Monocarboxylate transporter 12-B     1.81
 TRINITY DN71474 c7 g3 Na(+)/H(+) exchange regulatory cofactor NHE-RF1     2.64
 TRINITY DN74500 c2 g1 Na(+)/H(+) exchange regulatory cofactor NHE-RF3     1.94
 TRINITY DN79418 c0 g1 Niemann-Pick C1-like protein 1     2.65
 TRINITY DN76301 c3 g1 Niemann-Pick C1-like protein 1     1.85
 TRINITY DN75948 c4 g4 Phospholipid-transporting ATPase IA 2.26    
 TRINITY DN75214 c1 g9 Prolyl endopeptidase-like     1.85
 TRINITY DN77239 c2 g2 Sodium/hydrogen exchanger 7     4.65
 TRINITY DN67206 c1 g1 Sodium/myo-inositol cotransporter −3.06    −3.55
 TRINITY DN67731 c1 g1 Sodium/potassium-transporting ATPase subunit alpha-1   2.22   2.99
 TRINITY DN79640 c8 g1 Sodium-dependent neutral amino acid transporter B(0)AT1 2.83   2.7 3.96
 TRINITY DN71667 c2 g2 Sodium-dependent phosphate transport protein 2B    2.3 3.25
 TRINITY DN69556 c1 g3 Solute carrier family 13 member 2 2.15    2.78
 TRINITY DN60850 c0 g1 Solute carrier family 13 member 5 2.34   2.1 2.73
 TRINITY DN68059 c1 g4 Solute carrier family 15 member 1   1.78   
 TRINITY DN73228 c5 g1 Solute carrier family 2, facilitated glucose transporter member 2    2.56
 TRINITY DN72783 c3 g1 Solute carrier family 22 member 6   −3.83   
 TRINITY DN79648 c5 g9 Solute carrier family 40 member 1     2.60
 TRINITY DN73224 c8 g2 Zinc transporter 1     2.54
  1. Values correspond to fold changes between diets and the low fish meal control diet. Positive values indicate upregulation, and negative values down regulation. FM5 5% fish meal diet, FM20 20% fish meal diet, TH tilapia hydrolysate diet, SH shrimp hydrolysate diet, MH mixed hydrolysate diet