Dietary aquaculture by-product hydrolysates: impact on the transcriptomic response of the intestinal mucosa of European seabass (Dicentrarchus labrax) fed low fish meal diets

Leduc, Alexandre; Zatylny-Gaudin, Céline; Robert, Marie; Corre, Erwan; Corguille, Gildas Le; Castel, Hélène; Lefevre-Scelles, Antoine; Fournier, Vincent; Gisbert, Enric; Andree, Karl B.; Henry, Joël

doi:10.1186/s12864-018-4780-0

Table 5 Summary of differentially expressed genes related to cholesterol and long chain fatty acid pathways

From: Dietary aquaculture by-product hydrolysates: impact on the transcriptomic response of the intestinal mucosa of European seabass (Dicentrarchus labrax) fed low fish meal diets

Classification/Transcript		Gene fold change as compared to the low fish meal diet (FM5)
Classification/Transcript		FM20	FM5 + 5% TH	FM5 + 5% SH	FM5 + 5% MH
Cholesterol related
TRINITY DN71881 c0 g2	3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase				−3.00
TRINITY DN67458 c2 g3	Delta(14)-sterol reductase				−2.75
TRINITY DN76391 c4 g1	Farnesyl pyrophosphate synthase	−2.98		−2.7	−5.68
TRINITY DN71950 c2 g1	Hydroxymethylglutaryl-CoA synthase, cytoplasmic	−1.93			−3.19
TRINITY DN79342 c1 g2	Lanosterol 14-alpha demethylase	−1.85			−2.06
TRINITY DN75940 c1 g2	Lanosterol synthase	−2.65			−3.74
TRINITY DN76284 c0 g1	Lathosterol oxidase				−2.68
TRINITY DN72542 c3 g1	Neutral cholesterol ester hydrolase 1	2.61
TRINITY DN66926 c0 g1	Squalene monooxygenase				−3.82
TRINITY DN78143 c3 g1	Squalene synthase				−2.64
TRINITY DN71672 c0 g3	Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating				−3.59
TRINITY DN75298 c0 g2	Transmembrane protein 97				−2.25
Fatty acid related
TRINITY DN70866 c4 g9	2,4-dienoyl-CoA reductase, mitochondrial				−1.92
TRINITY DN78203 c0 g3	3-ketoacyl-CoA thiolase, mitochondrial				−2.37
TRINITY DN74534 c0 g3	Acetoacetyl-CoA synthetase				−4.95
TRINITY DN74255 c1 g3	Acetyl-CoA carboxylase				−2.11
TRINITY DN72189 c4 g3	Acyl-CoA desaturase	1.78			5.40
TRINITY DN70036 c1 g2	Alkylglycerol monooxygenase	1.99
TRINITY DN77637 c3 g4	ATP-binding cassette sub-family D member 2				−3.41
TRINITY DN74635 c4 g2	Elongation of very long chain fatty acids protein 4				−2.71
TRINITY DN73852 c1 g2	Elongation of very long chain fatty acids protein 6				−3.96
TRINITY DN79046 c1 g4	Fatty acid hydroxylase domain-containing protein 2				1.94
TRINITY DN79053 c1 g4	Fatty acid synthase				−3.33
TRINITY DN79341 c1 g1	Fatty acid-binding protein, brain	4.26
TRINITY DN56507 c0 g1	Fatty acid-binding protein, intestinal				−1.88
TRINITY DN79266 c1 g10	Fatty acid-binding protein, liver-type				−2.17
TRINITY DN78522 c0 g2	Long-chain-fatty-acid--CoA ligase 4	−1.89
TRINITY DN75220 c0 g3	Methylsterol monooxygenase 1	−2.26			−2.31
TRINITY DN78695 c0 g7	Perilipin-2	−3.04
TRINITY DN78695 c0 g2	Perilipin-2	−3.15		−2.3
TRINITY DN72627 c0 g1	Phosphatidate phosphatase LPIN1				−4.12
TRINITY DN72627 c1 g3	Phosphatidate phosphatase LPIN2	2.00
TRINITY DN71726 c1 g1	Sodium-dependent lysophosphatidylcholine symporter 1-B				−3.38
TRINITY DN72471 c1 g2	Trifunctional enzyme subunit beta, mitochondrial				−2.18
TRINITY DN67880 c1 g2	Very long-chain acyl-CoA synthetase			2.1	3.01
TRINITY DN71905 c5 g2	Very long-chain acyl-CoA synthetase	1.93
TRINITY DN76293 c0 g2	Very long-chain acyl-CoA synthetase	1.87

Values correspond to fold changes between diets and the low fish meal control diet. Positive values indicate upregulation, and negative values down regulation. FM5 5% fish meal diet, FM20 20% fish meal diet, TH tilapia hydrolysate diet, SH shrimp hydrolysate diet, MH mixed hydrolysate diet

Back to article page