Fig. 4

Reduction in symbiont’s ability to produce essential metabolites following removal of specific source metabolites (metabolites predicted to be available to the symbionts in the bacteriocyte) from the simulated host-environment. Only source metabolites whose removal affected at least one species are shown. P, C, H, R and W represent Portiera, Cardinium, Hamiltonella, Rickettsia and Wolbachia, respectively. Square strength color (white to dark green) represent the number of metabolites reduced from the network