Fig. 6From: Transcriptomics reveals the molecular processes of light-induced rapid darkening of the non-obligate cave dweller Oreolalax rhodostigmatus (Megophryidae, Anura) and their genetic basis of pigmentation strategySequence and structure change of MC1R and its implications in pigmentation of O. rhodostigmatus. a, Sequence analysis on the M/EJTD. Pink background indicates sites frequently occupied by basic residues. Missense mutations and amino acid deletions resulting melanic phenotypes were showed. b, Charges of this sequence fragment. c, 3D model of O. rhodostigmatus MC1R, with tandem aspartates highlighted. d, Sequences and charges of major agonists of MC1R. e, Structure of α-MSHBack to article page