Fig. 5

miRNA differential expression at isomiR level in colorectal neoplasia. Volcano plots of P-values against AUC demonstrated miRNA differential expression in (a) CRC and (b) advanced adenoma. Vertical dash lines indicate cutoff at AUC > 0.8 identifying those sequences with substantially unregulated expression. Lower panels indicate the AUC range of isomiRs among miRNAs with at least one isomiR with AUC > 0.8