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Fig. 5 | BMC Genomics

Fig. 5

From: High-resolution profiles of the Streptococcus mitis CSP signaling pathway reveal core and strain-specific regulated genes

Fig. 5

a Identification of early and late CSP-induced genes in S. mitis with no orthologues in S. pneumoniae. Presence and number of putative promoter sites are represented by black arrows. Fold-change induction values are presented as numbers on top of the pentagons. Orthologue genes are represented by the same color in both strains. b Real-Time PCR results regarding the expression of S. mitis type strain genes after the treatment with the pheromone compared to the untreated culture in a ΔsigX1ΔsigX2 derivative of the same strain (dashed bars) or the wild-type (filled bars). Controls for early genes were comA and comE; control for late gene was dprA. c Relative transformation efficiency of the S. mitis knockout strains for the competence-induced genes. a Positive control; b Negative control

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